Krabbe hastal\u0131\u011f\u0131 galaktozilseramidaz adl\u0131 enzim eksikli\u011finden kaynaklanmaktad\u0131r. Bu enzim eksikl\u011fi sinir h\u00fccrelerinin iletimini h\u0131zland\u0131ran miyelin k\u0131l\u0131f\u0131 olu\u015fturan h\u00fccrelerin geli\u015fimini olumsuz etkiler. Krabbe hastal\u0131\u011f\u0131 l\u00f6kodistrofik hastal\u0131klar olarak bilinen miyelin harabiyetine yol a\u00e7an hastal\u0131klar grubundad\u0131r. Krabbe hastal\u0131\u011f\u0131n\u0131n\u00a0 bir karakteristik \u00f6zelli\u011fi ise globoid h\u00fccrelerde art\u0131\u015f g\u00f6r\u00fclmesidir. Globoid h\u00fccreler beyinde bulunan anormal, geni\u015f ve genellikle birden fazla \u00e7ekirdek bulunduran h\u00fccrelerdir.<\/p>\n
\u0130LK SEMPTOMLAR: G\u00d6RME VE Y\u00dcR\u00dcME PROBLEMLER\u0130<\/b><\/p>\n
Semptomlar genelde bir ya\u015f\u0131ndan \u00f6nce g\u00f6r\u00fcl\u00fcr. Sinirlilik, kas zay\u0131fl\u0131\u011f\u0131, beslenme zorlu\u011fu, rahats\u0131zl\u0131k, enfeksiyon tabanl\u0131 olmayan gelip giden ate\u015f, v\u00fccut kat\u0131l\u0131\u011f\u0131, mental ve fiziksel geli\u015fim gerili\u011fi gibi tipik bulgular bar\u0131nd\u0131r\u0131r. Hastal\u0131k ilerledik\u00e7e kaslar zay\u0131flamaya, yemek, i\u00e7mek ve nefes almak zorla\u015fmaya ba\u015flamakla birlikte bebeklerde n\u00f6bet ve g\u00f6rme kayb\u0131 da g\u00f6r\u00fclebilmektedir.<\/p>\n
Daha az g\u00f6r\u00fclmekle birlikte semptomlar \u00e7ocukluk, ergenlik veya yeti\u015fkinlikte de ba\u015flayabilir. G\u00f6rme ve y\u00fcr\u00fcme problemleri ilk ve genel semptomlard\u0131r\u00a0 ama etkilenen ki\u015fiye g\u00f6re de de\u011fi\u015febilmektedir. Ge\u00e7 ba\u015flang\u0131\u00e7l\u0131 Krabbe hastal\u0131\u011f\u0131 olan ki\u015filer y\u0131llarca ya\u015fayabilmektedir.<\/p>\n","protected":false},"excerpt":{"rendered":"
Krabbe hastal\u0131\u011f\u0131 medikal ad\u0131yla globoid h\u00fccre l\u00f6kodistrofisi, sinir sistemini etkileyen dejeneratif bir hastal\u0131kt\u0131r.<\/p>\n","protected":false},"author":1,"featured_media":3914,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-3913","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik"],"_links":{"self":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts\/3913","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/comments?post=3913"}],"version-history":[{"count":1,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts\/3913\/revisions"}],"predecessor-version":[{"id":3915,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts\/3913\/revisions\/3915"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/media\/3914"}],"wp:attachment":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/media?parent=3913"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/categories?post=3913"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/tags?post=3913"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}