{"id":4087,"date":"2026-01-29T01:57:04","date_gmt":"2026-01-29T01:57:04","guid":{"rendered":"https:\/\/bihavadis.com\/?p=4087"},"modified":"2026-01-29T01:57:04","modified_gmt":"2026-01-29T01:57:04","slug":"losemi-nedir","status":"publish","type":"post","link":"https:\/\/bihavadis.com\/index.php\/2026\/01\/29\/losemi-nedir\/","title":{"rendered":"L\u00f6semi nedir"},"content":{"rendered":"

L\u00f6semiler h\u00fccre cinsine g\u00f6re ALL (Akut Lenfoblastik L\u00f6semi) ve AML (Akut Myeloblastik L\u00f6semi) olmak \u00fczere 2 ana gruba ayr\u0131l\u0131r. Kendi i\u00e7lerinde de alt s\u0131n\u0131flar tan\u0131mlanabilir. T\u00fcrkiye\u2019de her y\u0131l 16 ya\u015f\u0131n alt\u0131nda 1200-1500 yeni l\u00f6semili \u00e7ocuk vakas\u0131 bildirilmektedir.<\/p>\n

L\u00f6semi nedenleri hen\u00fcz tam olarak ayd\u0131nlat\u0131lmam\u0131\u015ft\u0131r. Sitogenetik ve molek\u00fcler tekniklerdeki yeni geli\u015fmelerle genetik yatk\u0131nl\u0131klar, radyasyon, benzen ve t\u00fcrevleri (bali, vs.), b\u00f6cek ila\u00e7lar\u0131 gibi kimyasal maddeler, baz\u0131 kal\u0131tsal hastal\u0131klar ve baz\u0131 viral hastal\u0131klar\u0131n hep birlikte l\u00f6semiye neden olduklar\u0131 \u00e7al\u0131\u015fmalarla g\u00f6sterilmi\u015ftir. L\u00f6semi her ya\u015fta g\u00f6r\u00fclmektedir. En s\u0131k \u00e7ocukluk \u00e7a\u011f\u0131nda 2-5 ya\u015flar\u0131nda artmaktad\u0131r. 1 ya\u015f\u0131n alt\u0131nda, 10 ya\u015f\u0131n \u00fcst\u00fcndeki yeni vakalarda tedaviye cevap azalmaktad\u0131r.<\/p>\n

Herhangi bir etkiyle damarlar\u0131m\u0131zda dola\u015fan kan\u0131n esas yap\u0131m yeri olan kemik ili\u011fimizdeki ana h\u00fccrelerde olu\u015fan \u015fifre de\u011fi\u015fikli\u011fi ile blast ad\u0131n\u0131 verilen olgun olmayan kan h\u00fccrelerinde art\u0131\u015f meydana gelmektedir. Bu h\u00fccreler h\u0131zla yay\u0131larak kemik ili\u011fini, lenf bezlerini, dala\u011f\u0131, karaci\u011feri, beyin ve merkezi sinir sistemini tutmaktad\u0131r.<\/span><\/p>\n

L\u00d6SEM\u0130 BEL\u0130RT\u0130LER\u0130<\/span><\/b><\/p>\n

\u00c7ocuklarda l\u00f6semi hastal\u0131\u011f\u0131n\u0131n ilk belirtileri:<\/span><\/span><\/p>\n

– \u0130\u015ftahs\u0131zl\u0131k<\/span><\/span><\/p>\n

\n
<\/div>\n<\/div>\n

– Kans\u0131zl\u0131k<\/span><\/span><\/p>\n

– Zay\u0131flama<\/span><\/span><\/p>\n

– Bacaklarda kemik a\u011fr\u0131lar\u0131<\/span><\/span><\/p>\n

– Cilt alt\u0131nda kanamalar<\/span><\/span><\/p>\n

– Burun ve di\u015f eti kanamalar\u0131<\/span><\/span><\/p>\n

– Ate\u015f<\/span><\/span><\/p>\n

Ayr\u0131ca yay\u0131ld\u0131\u011f\u0131 organlara ait belirtiler, \u00f6rne\u011fin ba\u015f a\u011fr\u0131s\u0131, kusma, kar\u0131n a\u011fr\u0131s\u0131, g\u00f6rme bozukluklar\u0131 \u00f6nem ta\u015f\u0131yabilir. Bu yak\u0131nmalarla m\u00fcracaat ettikleri \u00e7ocuk hematoloji (kan hastal\u0131klar\u0131) uzmanlar\u0131nca yap\u0131lan muayenede \u00e7o\u011funlukla karaci\u011fer ve dalak b\u00fcy\u00fcmesi, lenf bezlerinde geni\u015fleme, kanama bulgular\u0131 tespit edilebilir. Yap\u0131lan kan, kemik ili\u011fi, h\u00fccre tipini belirleme ve genetik tetkikler sonucu kesin tan\u0131 konulabilir. Tan\u0131daki ayr\u0131nt\u0131l\u0131 testler genellikle l\u00f6semi tiplerini, tedavi prensiplerini belirlemede yard\u0131mc\u0131 olacakt\u0131r.<\/p>\n

TEDAV\u0130<\/b><\/p>\n

Tedavi \u00f6ncelikle genel durumun d\u00fczeltilmesi y\u00f6ntemleri ile ba\u015flar. Bu safhada kan veya kan\u0131n i\u00e7indeki \u00f6zel h\u00fccrelerini don\u00f6rlerden (g\u00f6n\u00fcll\u00fc kan verici ki\u015fi) al\u0131narak l\u00f6semili hastaya verilmesi, enfeksiyon mevcutsa gerekli m\u00fccadelelerin yap\u0131lmas\u0131, b\u00f6breklerin, karaci\u011fer ve kalbin kemoterapi ila\u00e7lar\u0131n\u0131n yan etkilerinden korunma \u00f6nlemlerinin al\u0131nmas\u0131 \u00e7ok \u00f6nemlidir.<\/p>\n

Ayr\u0131ca hastalar\u0131n ve ailelerin hastal\u0131k hakk\u0131nda bilgilendirilmesi, l\u00f6seminin umutsuz de\u011fil, tersine iyi bir tedavi ve moral deste\u011fi ile l\u00f6semide y\u00fczde 85\u2019lere varan oranda iyile\u015fmenin sa\u011fland\u0131\u011f\u0131n\u0131n a\u00e7\u0131klanmas\u0131 tedavinin ikinci basama\u011f\u0131d\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u00c7ocukluk \u00e7a\u011f\u0131ndaki kanser vakalar\u0131n\u0131n y\u00fczde 35’ini l\u00f6semiler olu\u015fturur ve birinci s\u0131radad\u0131r.<\/p>\n","protected":false},"author":1,"featured_media":4088,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[605,577],"class_list":["post-4087","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-hucre","tag-tedavi"],"_links":{"self":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts\/4087","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/comments?post=4087"}],"version-history":[{"count":1,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts\/4087\/revisions"}],"predecessor-version":[{"id":4089,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts\/4087\/revisions\/4089"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/media\/4088"}],"wp:attachment":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/media?parent=4087"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/categories?post=4087"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/tags?post=4087"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}