Ege \u00dcniversitesi Solunum Ara\u015ft\u0131rmalar\u0131 Merkezi\u2019nden (EgeSAM) yard\u0131mc\u0131 ara\u015ft\u0131rmac\u0131 Dr. Esra Atalay \u015eahar\u2019\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131 proje T\u00dcB\u0130TAK Bireysel Gen\u00e7 Giri\u015fim \u201cB\u0130GG\u201d program\u0131 2024 y\u0131l\u0131 birinci d\u00f6nem \u00e7a\u011fr\u0131s\u0131 kapsam\u0131nda hibe almaya hak kazand\u0131.<\/p>\n
Ege Teknopark ve EB\u0130LTEM i\u015fbirli\u011fi ile y\u00fcr\u00fct\u00fclen BiGG-Ege Program\u0131 alt\u0131nda, T\u00dcB\u0130TAK\u2019\u0131n ikinci a\u015fama panel de\u011ferlendirmesinde desteklenen projelerden birisi de Dr. Esra Atalay \u015eahar\u2019\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131 proje oldu. Proje ile d\u00fcnya \u00e7ap\u0131nda milyonlarca insan i\u00e7in yayg\u0131n sa\u011fl\u0131k sorunu olu\u015fturan ve ya\u015fam kalitesini d\u00fc\u015f\u00fcren alerji hastal\u0131\u011f\u0131na y\u00f6nelik, piyasadaki y\u00f6ntemlerine g\u00f6re daha ucuz, daha h\u0131zl\u0131 ve kesin tan\u0131 koyabilen alerji tan\u0131 kiti \u00fcretilecek.<\/p>\n
Dr. Esra Atalay \u015eahar\u2019\u0131 makam\u0131nda a\u011f\u0131rlayarak tebrik eden Ege \u00dcniversitesi Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak, \u201cTam akredite, \u00f6\u011frenci odakl\u0131 \u00f6nc\u00fc ara\u015ft\u0131rma \u00fcniversitemiz bilim insanlar\u0131 insanl\u0131\u011f\u0131n sorunlar\u0131na \u00e7\u00f6z\u00fcm \u00fcreten yenilik\u00e7i projeler \u00fcretmeye devam ediyorlar. Yerli ve milli bir anlay\u0131\u015fla \u00fcretilen projelerin desteklenmesi, somut bir \u00e7\u0131kt\u0131ya d\u00f6n\u00fc\u015fmesi ve katma de\u011fer \u00fcretmesi bizleri ziyadesiyle mutlu ediyor. Dr. Esra Atalay \u015eahar hocam\u0131z\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131 proje T\u00dcB\u0130TAK\u2019tan destek almaya hak kazand\u0131. Proje kapsam\u0131nda yerli ve milli imk\u00e2nlarla piyasadaki y\u00f6ntemlere g\u00f6re daha ucuz, daha h\u0131zl\u0131 ve kesin tan\u0131 koyabilen alerji kiti geli\u015ftirilecek. \u00dclkemizde ilk defa \u00fcniversitemiz b\u00fcnyesinde yerli imk\u00e2nlarla geli\u015ftirilecek kit sayesinde bu alandaki d\u0131\u015fa ba\u011f\u0131ml\u0131l\u0131k azalt\u0131lacak.\u00a0 \u00c7ok \u00f6nemli buldu\u011fum bu projeyi hayata ge\u00e7iren ba\u015fta proje y\u00fcr\u00fct\u00fcc\u00fcs\u00fc Dr. Esra Atalay \u015eahar hocam\u0131z olmak \u00fczere b\u00fct\u00fcn proje ekibini tebrik ediyor, \u00e7al\u0131\u015fmalar\u0131nda ba\u015far\u0131lar diliyorum\u201d dedi.<\/p>\n
\u201cAlerji d\u00fcnya \u00e7ap\u0131nda her ya\u015ftan insan\u0131 etkileyen bir rahats\u0131zl\u0131k\u201d<\/b><\/p>\n
Projenin i\u00e7eri\u011fi ile ilgili bilgi veren Dr. Esra Atalay \u015eahar,\u00a0 \u201cDe\u011fi\u015fen ya\u015fam tarzlar\u0131, artan \u00e7evresel kirlilik, kentle\u015fme ve sigara i\u00e7mek gibi sa\u011fl\u0131ks\u0131z al\u0131\u015fkanl\u0131klar alerjik hastal\u0131klar\u0131n artmas\u0131na neden olmaktad\u0131r. End\u00fcstriyelle\u015fen d\u00fcnya, artan \u00e7evresel kirlilik ve kentle\u015fmeye ba\u011fl\u0131 olarak ger\u00e7ekle\u015fen iklim de\u011fi\u015fikli\u011fi; bitkilerin daha h\u0131zl\u0131 b\u00fcy\u00fcmesine neden olarak erken \u00e7i\u00e7eklenme ve tozla\u015fmay\u0131 sa\u011flamakta, d\u00f6nemsel polen miktar\u0131n\u0131n artmas\u0131na neden olarak, solunum yolu alerjilerini dolayl\u0131 olarak etkilemektedir. Alerjik hastal\u0131klar d\u00fcnya \u00e7ap\u0131nda milyonlarca insan i\u00e7in yayg\u0131n sa\u011fl\u0131k sorunudur ve genel n\u00fcfusun y\u00fczde 30’unu etkilemektedir. D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc’n\u00fcn Ocak 2023’te yay\u0131nlad\u0131\u011f\u0131 istatistiklere g\u00f6re, ABD’de yakla\u015f\u0131k 4 \u00e7ocuktan 1’i ve 3 yeti\u015fkinden 1’i mevsimsel alerjiye sahiptir. Alerji d\u00fcnya \u00e7ap\u0131nda her ya\u015ftan insan\u0131 etkileyen, \u00f6zellikle de sanayile\u015fen \u00fclkelerde \u00f6nemli bir sa\u011fl\u0131k ve sosyoekonomik problemdir. Avrupa \u00fclkelerinde yap\u0131lan ara\u015ft\u0131rma do\u011frultusunda toplumun y\u00fczde 40\u2019\u0131 bu hastal\u0131ktan etkilenirken y\u00fczde 70 \u00e7oklu duyarl\u0131l\u0131k g\u00f6stermektedir. \u00c7ocuklarda ise atopik dermatit, alerjik rinit ve alerjik ast\u0131m tan\u0131s\u0131 s\u0131kl\u0131kla konmaktad\u0131r. Alerjik reaksiyonlar ya\u015fam kalitesinin d\u00fc\u015fmesinin yan\u0131 s\u0131ra ast\u0131m ataklar\u0131 gibi ciddi hastal\u0131klara da yol a\u00e7maktad\u0131r. Bu nedenle alerjiye neden olan alerjen tan\u0131s\u0131n\u0131n do\u011fru ve h\u0131zl\u0131 bir \u015fekilde tan\u0131mlanmas\u0131 maruziyeti azaltacak \u00f6nlemin yan\u0131 s\u0131ra optimum ve etkili tedavi a\u00e7\u0131s\u0131ndan b\u00fcy\u00fck \u00f6nem ta\u015f\u0131maktad\u0131r\u201d dedi.<\/p>\n
\u201cTan\u0131 ve tedavide pek \u00e7ok kolayl\u0131k sa\u011flayacak\u201d<\/b><\/p>\n
Dr. Esra Atalay \u015eahar,\u00a0 \u201cGeli\u015ftirmeyi planlad\u0131\u011f\u0131m\u0131z ileri molek\u00fcler y\u00f6ntemlerin kullan\u0131ld\u0131\u011f\u0131 alerji kitinin tek bir testte spesifitesi y\u00fcksek, h\u0131zl\u0131 ve piyasadaki emsallerine g\u00f6re daha ucuz bir \u00fcr\u00fcn olmas\u0131n\u0131 hedeflemekteyiz. Geleneksel y\u00f6ntemlerden olan deri prick testinde deride k\u00fc\u00e7\u00fck bir i\u011fnenin bat\u0131r\u0131larak alerjene maruz b\u0131rak\u0131lmas\u0131yla tan\u0131 konmaktad\u0131r. Bu tan\u0131 y\u00f6nteminin antihistaminik kullanan hastalarda yanl\u0131\u015f negatif sonuca neden olmas\u0131, alerjen ekstrakt\u0131n\u0131n tamam\u0131n\u0131n uygulanmas\u0131 \u00e7apraz reaksiyonlara neden olarak yanl\u0131\u015f pozitif sonu\u00e7 g\u00f6zlemlenmesi, potansiyel anafilaktik reaksiyon riski ta\u015f\u0131mas\u0131, yayg\u0131n egzamas\u0131 olan ki\u015filer i\u00e7in ideal bir y\u00f6ntem olmamas\u0131 gibi dezavantajlar\u0131 bulunmaktad\u0131r. Klasik y\u00f6ntemlerden deri prick testine ek olarak, kandan spesifik IgE belirlenmesiyle ekstrakt tabanl\u0131 alerjenler kullan\u0131larak da tan\u0131 konmaktad\u0131r. Bu y\u00f6ntemin ise hassasiyetinin az olmas\u0131n\u0131n yan\u0131 s\u0131ra deri prick testine benzer \u015fekilde alerjen ekstrakt\u0131n\u0131n tamam\u0131n\u0131n uygulanmas\u0131 nedeniyle \u00e7apraz reaksiyon olu\u015fturma riski bulunmaktad\u0131r\u201d diye konu\u015ftu.<\/p>\n
\u201cYerli \u00fcretim ile d\u0131\u015fa ba\u011f\u0131ml\u0131l\u0131\u011f\u0131n \u00f6n\u00fcne ge\u00e7ilecek\u201d<\/b><\/p>\n
Molek\u00fcler y\u00f6ntemlerle yap\u0131lan te\u015fhislerin, geleneksel te\u015fhisleri tamamlayarak optimum hasta y\u00f6netimi ve etkili tedaviye olanak sa\u011flad\u0131\u011f\u0131n\u0131 belirten Dr. Esra Atalay \u015eahar,\u00a0 \u201c\u015euan tan\u0131 amac\u0131yla piyasada kullan\u0131lmakta olan molek\u00fcler y\u00f6ntemler ise olduk\u00e7a pahal\u0131 y\u00f6ntemlerdir. Bu durum b\u00f6yle kitlerin t\u00fcm hastane ve laboratuvarlarda kullan\u0131lmas\u0131n\u0131 k\u0131s\u0131tlamaktad\u0131r. Yerli \u00fcretimde ise bu \u00f6zelliklere sahip bir tan\u0131 testi bulunmamaktad\u0131r. Bizim geli\u015ftirmeyi planlad\u0131\u011f\u0131m\u0131z tan\u0131 kitiyle piyasadaki tan\u0131 y\u00f6ntemlerine g\u00f6re daha ucuz, h\u0131zl\u0131 ve kesin tan\u0131 konmas\u0131 ama\u00e7lanmaktad\u0131r. Ayr\u0131ca yerli \u00fcretim olmas\u0131 nedeniyle de d\u0131\u015far\u0131ya ba\u011f\u0131ml\u0131l\u0131\u011f\u0131n \u00f6n\u00fcne ge\u00e7ilmi\u015f olunacakt\u0131r. Piyasadaki benzerlerimize g\u00f6re yerli \u00fcretilecek olmas\u0131 nedeniyle daha ucuza mal edilebilir olmas\u0131 say\u0131lan t\u00fcm konforlar\u0131 sa\u011flamas\u0131n\u0131n yan\u0131nda en b\u00fcy\u00fck avantaj\u0131m\u0131z olarak g\u00f6r\u00fclmektedir\u201d dedi.<\/p>\n
\u201cT\u00fcrkiye\u2019de ilk kez Ege \u00dcniversitesi b\u00fcnyesinde geli\u015ftirilecek\u201d<\/b><\/p>\n
T\u00fcrkiye\u2019de piyasada bulunan ticari antijenlerden farkl\u0131 \u00f6zellikte antijenleri de i\u00e7erecek \u015fekilde bir kitin ilk kez Ege \u00dcniversitesi b\u00fcnyesinde geli\u015ftirilece\u011fini vurgulayan Dr. Esra Atalay \u015eahar,\u00a0\u00a0 \u201cAlerji alan\u0131ndaki T\u00fcrkiye genelinde kritik \u00f6neme sahip \u00fcr\u00fcnlerden birini geli\u015ftirebilmeyi; uluslararas\u0131 i\u015fbirlikleri ile de \u00fclkemize katma de\u011fer sa\u011flayan, alan\u0131nda \u00f6nc\u00fcl \u015firketlerden biri olmay\u0131 hedeflemekteyiz. Piyasada bulunan benzerlerimizden farkl\u0131 olarak az say\u0131daki hastalarda alerji, a\u011f\u0131r ast\u0131m ataklar\u0131 ya da anafilaksiye neden olan ve bu nedenle piyasada bulunan ticari antijenlerden farkl\u0131 \u00f6zellikte antijenleri de i\u00e7erecek \u015fekilde tan\u0131 kitlerini \u00fclkemiz i\u00e7in ilk kez Ege \u00dcniversitesi b\u00fcnyesinde geli\u015ftirerek yerli \u00fcretmek \u00f6ncelikli hedeflerimiz aras\u0131nda yer almaktad\u0131r\u201d diye konu\u015ftu.<\/p>\n
Kaynak: (BYZHA) Beyaz Haber Ajans\u0131<\/p>\n","protected":false},"excerpt":{"rendered":"
Ege \u00dcniversitesi Solunum Ara\u015ft\u0131rmalar\u0131 Merkezi\u2019nden (EgeSAM) yard\u0131mc\u0131 ara\u015ft\u0131rmac\u0131 Dr. Esra Atalay \u015eahar\u2019\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131 proje T\u00dcB\u0130TAK Bireysel Gen\u00e7 Giri\u015fim \u201cB\u0130GG\u201d program\u0131 2024 y\u0131l\u0131 birinci d\u00f6nem \u00e7a\u011fr\u0131s\u0131 kapsam\u0131nda hibe almaya hak kazand\u0131.<\/p>\n","protected":false},"author":1,"featured_media":5201,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[575,467,237,1122,777],"class_list":["post-5200","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-gundem","tag-alerji","tag-hasta","tag-proje","tag-tani","tag-yontem"],"_links":{"self":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts\/5200","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/comments?post=5200"}],"version-history":[{"count":1,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts\/5200\/revisions"}],"predecessor-version":[{"id":5202,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/posts\/5200\/revisions\/5202"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/media\/5201"}],"wp:attachment":[{"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/media?parent=5200"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/categories?post=5200"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bihavadis.com\/index.php\/wp-json\/wp\/v2\/tags?post=5200"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}